Description
Product Characteristics:
Aliases: CTLA 8 antibody, CTLA-8 antibody, CTLA8 antibody, cytotoxic T lymphocyte associated antigen 8 antibody, Cytotoxic T lymphocyte associated protein 8 antibody, Cytotoxic T lymphocyte associated serine esterase 8 antibody, Cytotoxic T-lymphocyte-associated antigen 8 antibody, IL 17 antibody, IL 17A antibody, IL-17 antibody, IL-17A antibody, IL17 antibody, IL17_HUMAN antibody, Il17a antibody, Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8) antibody, interleukin 17A antibody, Interleukin-17A antibody, interleukin17 antibody, Interleukin17A antibody, OTTHUMP00000016597 antibody, OTTMUSP00000046003 antibody
Target Information: The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]